Acitretin for Children: Is It a Safe Treatment Option?

Acitretin for Children: Is It a Safe Treatment Option?

Understanding Acitretin and Its Uses

Before we delve into the topic of Acitretin for children, it is essential to understand what Acitretin is and its primary uses. Acitretin is a retinoid, which is a class of medications that are derived from vitamin A. It is primarily prescribed to treat severe psoriasis, a chronic skin condition characterized by red, scaly patches on the skin. Acitretin works by slowing down the rapid growth and shedding of skin cells, which helps alleviate the symptoms of psoriasis.


Although Acitretin has been proven to be effective in treating psoriasis, it is generally reserved for cases where other treatments have failed, due to its potential side effects. So, the question arises - is Acitretin a safe treatment option for children? Let's explore this subject in detail through the following sections.

Acitretin for Children: Safety Concerns

One of the primary concerns regarding the use of Acitretin in children is its potential side effects. Some of the common side effects include dry skin, chapped lips, hair loss, and increased sensitivity to sunlight. In some cases, Acitretin may cause more severe side effects, such as liver damage, high cholesterol levels, and bone or joint pain.


Another significant concern is the risk of birth defects associated with Acitretin. Women who are pregnant or planning to become pregnant are strongly advised against using Acitretin due to its potential to cause severe birth defects. Therefore, it is crucial to consider the safety concerns associated with Acitretin before considering it as a treatment option for children.

Acitretin for Children: Efficacy

Several studies have evaluated the efficacy of Acitretin in treating psoriasis in children. In general, these studies have found that Acitretin can be an effective treatment option for children with severe psoriasis who have not responded to other treatment methods. However, the response to Acitretin varies among individuals, and not all children may experience significant improvement in their symptoms.


It is essential to weigh the potential benefits of Acitretin against the potential risks and side effects when considering it as a treatment option for a child with psoriasis. A thorough discussion with the child's healthcare provider is necessary to determine if Acitretin is the right choice for the child.

Monitoring and Follow-up

If a child is prescribed Acitretin, it is crucial to closely monitor and follow up with the child's healthcare provider. Regular blood tests may be required to monitor liver function, cholesterol levels, and other potential side effects of the medication. Additionally, the child's healthcare provider may need to adjust the dosage of Acitretin to find the most effective and safe dose for the child.


Parents and caregivers should also be vigilant in monitoring the child for any potential side effects and report any concerns to the child's healthcare provider. Promptly addressing any side effects or concerns can help ensure the child's safety while using Acitretin.

Alternative Treatment Options

Given the potential risks and side effects associated with Acitretin, it is essential to consider alternative treatment options for children with psoriasis. Other treatment options may include topical medications, phototherapy, and biologic medications. The child's healthcare provider can help determine the most appropriate treatment option based on the child's individual needs and circumstances.


It is also crucial for parents and caregivers to educate themselves about the various treatment options available and actively participate in the decision-making process. This can help ensure the child receives the most effective and safe treatment for their condition.

Acitretin for Children: The Importance of Informed Decision-Making

Ultimately, the decision to use Acitretin as a treatment option for a child with psoriasis should be made after careful consideration of the potential risks and benefits. Parents and caregivers should have open and honest conversations with the child's healthcare provider to ensure they are making informed decisions about the child's treatment.


It is also essential for parents and caregivers to provide the necessary support and encouragement for the child throughout their treatment journey. This can help the child better cope with their condition and improve their overall quality of life.

Conclusion

In conclusion, Acitretin can be a viable treatment option for children with severe psoriasis who have not responded to other treatments. However, the potential risks and side effects of the medication must be carefully weighed against the potential benefits. Parents and caregivers should work closely with the child's healthcare provider to determine the best course of action and provide the necessary support and care for the child throughout their treatment journey.

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Comments (18)

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    Gary Fitsimmons

    April 28, 2023 AT 08:52
    Ive seen kids on this stuff and honestly it breaks my heart seeing them with cracked lips and peeling skin all the time
    they need better options
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    Bob Martin

    April 28, 2023 AT 10:23
    so you mean the same drug that gets women banned from pregnancy for 3 years is okay for 8 year olds who might grow up to be 18 year olds who might want babies someday
    brilliant logic
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    Sage Druce

    April 29, 2023 AT 01:14
    My nephew was on acitretin for two years and we had to do monthly blood work and sunscreen like its his job
    he still got sunburned twice
    but his skin cleared up and he started playing soccer again so i dont regret it
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    Tyler Mofield

    April 30, 2023 AT 00:41
    The pharmacokinetic profile of acitretin demonstrates significant hepatic metabolism via cytochrome P450 pathways and prolonged half-life due to enterohepatic recirculation
    pediatric dosing requires stringent therapeutic drug monitoring to mitigate hepatotoxicity and hyperlipidemia risks
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    Patrick Dwyer

    April 30, 2023 AT 14:07
    In clinical practice we always start with topical calcineurin inhibitors and narrowband UVB before considering systemic retinoids
    the risk-benefit calculus in pediatrics is extremely delicate
    parental education is non-negotiable
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    Bart Capoen

    May 1, 2023 AT 04:53
    i read somewhere that acitretin can stay in your system for years
    like literally your bones store it
    so if your kid takes it at 10 and gets pregnant at 25
    good luck
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    luna dream

    May 1, 2023 AT 14:27
    they dont want you to know this but acitretin was originally developed by the same company that made Agent Orange
    its not about psoriasis its about control
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    Linda Patterson

    May 2, 2023 AT 01:51
    America needs to stop letting big pharma poison our children with this junk
    we have better medicine in India and they dont use this crap
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    Jen Taylor

    May 2, 2023 AT 15:51
    Ive been a pediatric dermatology nurse for 17 years... and I can tell you that when everything else fails, acitretin can be a lifeline. But it's not a magic pill-it's a marathon. You need weekly check-ins, moisturizers like it's oxygen, and a whole lot of patience. And yes, the lip balm budget? It's real.
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    Shilah Lala

    May 3, 2023 AT 00:13
    So we're just gonna give a kid a chemical that makes their skin fall off and hope they dont get pregnant in 15 years?
    what a time to be alive
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    Christy Tomerlin

    May 3, 2023 AT 14:57
    If your kid has psoriasis you probably didnt feed them right anyway
    stop blaming the drug and start blaming the junk food
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    Susan Karabin

    May 3, 2023 AT 18:55
    We treat symptoms but we never ask why the body is doing this in the first place
    skin is a mirror
    what is your child stressed about
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    Lorena Cabal Lopez

    May 4, 2023 AT 05:28
    I dont trust doctors who push this drug
    they just want to check a box
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    Stuart Palley

    May 4, 2023 AT 14:58
    My cousin took this as a teen and now she cant have kids
    and she still has psoriasis
    so what was the point
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    Glenda Walsh

    May 4, 2023 AT 19:24
    Did you know that acitretin can also cause depression and suicidal thoughts in children? I read it on a forum. Someone said their kid cried all night after starting it. I just think we need to be more careful. Like, really careful. Like, call your senator careful.
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    Tanuja Santhanakrishnan

    May 5, 2023 AT 09:00
    In India we use neem oil, turmeric paste, and sunlight therapy first
    many kids improve without chemicals
    acitretin is like using a sledgehammer to crack a nut
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    Raj Modi

    May 5, 2023 AT 20:53
    The therapeutic efficacy of acitretin in pediatric psoriasis is well-documented in peer-reviewed literature including the Journal of the American Academy of Dermatology, 2019 meta-analysis, which reports a 68% reduction in PASI scores with sustained use over 12 months
    however, the incidence of elevated liver enzymes and triglycerides necessitates rigorous biochemical surveillance protocols
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    Cecil Mays

    May 6, 2023 AT 16:35
    My son was on this for a year and we had to buy 3 tubes of lip balm a week 😅
    but he smiled again
    so worth it 💪❤️

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